THE SCIENCE

A breakthrough for brain health

Neurogen combines groundbreaking testing technology with the expertise of world-class neurologists and researchers to offer a revolutionary new approach to brain health.

The Basics

Assessing a person's brain health can be complicated. Here are some basic factors to keep in mind.

OF OLDER AMERICANS

living with mild cognitive impairment receive a diagnosis.

Alzheimer's vs. Dementia

Dementia is a term for a range of symptoms affecting cognitive abilities, such as memory, language, and behavior. Alzheimer's is the most common type of dementia, accounting for 60-80% of all diagnoses.1

Symptoms


Progression


Causes

Early detection right at home

We use a short online cognitive assessment and a simple at-home blood test to support the early detection of Alzheimer's.

Revolutionary testing technology

P-tau217 is a blood biomarker for Alzheimer's that starts to build up years before symptoms appear. Testing for this protein allows earlier detection of the disease.

Our testing method is highly accurate, providing clinical quality results from an at-home blood sample.

This blood test performs as well as the current standard of care (PET-scans) at a fraction of the cost.

Early detection gives you time to act

When Alzheimer's is detected early, you have more time to take proactive steps to better protect and care for your cognitive health.

Lifestyle
Changes

Slowing Disease
Progression

New Detection
Methods

Treatment
Options

Develop a
Care Plan

Maintain
Independence

Lifestyle Changes

You can reduce your risk of cognitive decline by up to 60% by making healthy changes in your lifestyle. Some key lifestyle factors are smoking, drinking, physical activity, sleep, and diet.

One-of-a-kind testing and exceptional care

At Neurogen, we're committed to partnering with you to improve the care surrounding Alzheimer's. That's why we've created an entire ecosystem of care, from earlier detection to connecting our patients to some of the best neurologists and Alzheimer's experts in the world.

Led by scientists

Our leaders are experts in neurology, dementia care and life sciences innovation. Their mission is to ensure that more patients have access to the highest quality care.

Dr. Rany Aburashed

Dr. Rany Aburashed

CEO & Founder

  • Over 15 years expertise in neurology and neuroimmunology, coupled with a proven track record of leadership in clinical care and healthcare systems.
  • Combines dedication to patient care as Chief Medical Officer of Insight Corporation with a commitment to advancing innovative diagnostic solutions for neurodegenerative diseases.
  • Has led numerous clinical trials, contributing to breakthroughs in the treatment of multiple sclerosis and related conditions.
  • Combines big-picture ambition with a focus on sustainable and effective solutions that improve lives and redefine the standards of patient care.
Dr. Elisabeth Thijssen

Dr. Elisabeth Thijssen

Chief Scientific Officer

  • Leads Neurogen’s scientific vision, leveraging over a decade of expertise in neurodegenerative research and biomarker innovation.
  • Her groundbreaking work on Alzheimer’s blood tests, featured in Nature Medicine and The Lancet Neurology, has redefined early detection of the disease.
  • Has led high-impact R&D and business initiatives across consulting and biotech, forging innovative solutions and strategic partnerships that drive meaningful impact.
  • Holds a Cum Laude PhD in Neurochemistry of Alzheimer's Disease, a Master's in Pharmaceutical Sciences, and a Bachelor's in Biomedical Sciences.
Dr. Kenneth Bahk

Dr. Kenneth Bahk

Chief Strategy Officer

  • Shapes Neurogen’s strategic vision, bringing decades of experience in healthcare innovation, investment, and ecosystem building.
  • Accomplishments include founding, building, and investing in transformative diagnostic and life science startups, achieving multiple market-leading exits.
  • Has driven impactful R&D, policy, and business initiatives with organizations including the White House, JP Morgan, the Mayo Clinic, as well as leading professional groups in laboratory medicine and innovation.
  • Holds an MS in Neurobiology, a PhD in Biochemistry and Molecular Biology, and an MBA from Northwestern University.

"The current landscape of Alzheimer's diagnosis remains reactionary and often a diagnosis is made quite late. This puts us at a massive disadvantage in addressing our modifiable risk factors, gaining access to disease-modifying therapies in time, and guidance towards cutting-edge clinical trials when patients remain clinically eligible. Our goal at Neurogen Biomarking is to close this gap and help guide patients into the broader ecosystem in the most clinically and scientifically accurate way at a significantly earlier time."

- Dr. Rany Aburashed

References

1 What is Alzheimer's Disease? Alzheimer's Association. https://www.alz.org/alzheimers-dementia/what-is-alzheimers

2 Mild Cognitive Impairment (MCI) Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/symptoms-causes/syc-20354578

3 Alzheimer's Disease, Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/symptoms-causes/syc-20350447

4 Stages of Alzheimer's. Alzheimer's Association. https://www.alz.org/alzheimers-dementia/stages

5 Dhana K, et al. Healthy lifestyle and the risk of Alzheimer's dementia: Findings from two longitudinal studies. Neurology. 2020; 95:1-10. doi: 10>1212/WNL. 0000000000009816

6 Preventing Alzheimer's Disease: What Do We Know? National Institute on Aging. https://www.nia.nih.gov/health/alzheimers-and-dementia/preventing-alzheimers-disease-what-do-we-know

7 Mielke (2024) Recommendations for clinical implementation of blood-based biomarkers for Alzheimer's disease.

8 McDade (2022) - Clinical Trial Alzheimers Res Ther. 2022 Dec 21;14(1):191. doi: 10.1186/s13195-022-01124-2. Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study.

9 Pontecorvo (2022) - JAMA Neurol. 2022;79(12):1250-1259. doi:10.1001/jamaneurol.2022.3392

10 Cummings (2024) - Alzheimer's disease drug development pipeline: 2024